Semantic MEDLINE

Semantic MEDLINE is a web application that summarizes MEDLINE citations returned by a PubMed search [1, 2]. Natural language processing is used to extract semantic predications from titles and abstracts. The predications are presented in a graph that has links to the MEDLINE text processed.

To access Semantic MEDLINE, click here. Please note that a free license for the Unified Medical Language System is required to access Semantic MEDLINE. The license agreement is available at this site. A quick tour video explaining Semantic MEDLINE can be watched here.

In using Semantic MEDLINE, begin at the Search tab by issuing a PubMed query; then move to the Summarize tab. Choose a topic to specify one of the four points of view of the summary: Treatment of Disease, Substance Interactions, Diagnosis, or Pharmacogenomics. After selecting the topic of the summary, click on the Summarize and Visualize button to display a graph representing the summarized predications. The nodes in the graph represent concepts and the edges that link the nodes correspond to the relations of the predications and establish the binding relationships between the concepts (arguments). Clicking on an edge and then on the Citations button located at the lower right corner will display the PubMed citations from which the predications were extracted.


  1. Kilicoglu, H. et al. (2008). Semantic MEDLINE: A Web application to manage the results of PubMed searches. Proceedings, Third International Symposium on Semantic Mining in Biomedicine (SMBM 2008), 69-76.
  2. Rindflesch, T.C. et al. (2011) Semantic MEDLINE: An advanced information management aplication for biomedicine. Information Services & Use, 31, 15-21.